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1hh0

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[[Image:1hh0.gif|left|200px]]
 
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==Filamentous Bacteriophage PH75==
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The line below this paragraph, containing "STRUCTURE_1hh0", creates the "Structure Box" on the page.
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<StructureSection load='1hh0' size='340' side='right'caption='[[1hh0]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1hh0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_phage_PH75 Thermus phage PH75]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1HH0 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Fiber diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1hh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hh0 OCA], [https://pdbe.org/1hh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1hh0 RCSB], [https://www.ebi.ac.uk/pdbsum/1hh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1hh0 ProSAT]</span></td></tr>
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{{STRUCTURE_1hh0| PDB=1hh0 | SCENE= }}
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</table>
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== Function ==
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'''FILAMENTOUS BACTERIOPHAGE PH75'''
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[https://www.uniprot.org/uniprot/CAPSD_BPH75 CAPSD_BPH75]
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__TOC__
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</StructureSection>
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==Overview==
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[[Category: Large Structures]]
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The PH75 strain of filamentous bacteriophage (Inovirus) grows in the thermophilic bacterium Thermus thermophilus at 70 degrees C. We have characterized the viral DNA and determined the amino acid sequence of the major coat protein, p8. The p8 protein is synthesized without a leader sequence, like that of bacteriophage Pf3 but unlike that of bacteriophage Pf1, both of which grow in the mesophile Pseudomonas aeruginosa. X-ray diffraction patterns from ordered fibres of the PH75 virion are similar to those from bacteriophages Pf1 and Pf3, indicating that the protein capsid of the PH75 virion has the same helix symmetry and subunit shape, even though the primary structures of the major coat proteins are quite different and the virions assemble at very different temperatures. We have used this information to build a molecular model of the PH75 protein capsid based on that of Pf1, and refined the model by simulated annealing, using fibre diffraction data extending to 2.4 A resolution in the meridional direction and to 3.1 A resolution in the equatorial direction. The common design may reflect a fundamental motif of alpha-helix packing, although differences exist in the DNA packaging and in the means of insertion of the major coat protein of these filamentous bacteriophages into the membrane of the host bacterial cell. These may reflect differences in the assembly mechanisms of the virions.
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[[Category: Thermus phage PH75]]
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[[Category: Marvin DA]]
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==About this Structure==
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[[Category: Pederson DM]]
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1HH0 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Thermus_phage_ph75 Thermus phage ph75]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HH0 OCA].
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[[Category: Perham RN]]
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[[Category: Sampson M]]
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==Reference==
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[[Category: Slater MR]]
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The protein capsid of filamentous bacteriophage PH75 from Thermus thermophilus., Pederson DM, Welsh LC, Marvin DA, Sampson M, Perham RN, Yu M, Slater MR, J Mol Biol. 2001 Jun 1;309(2):401-21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/11371161 11371161]
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[[Category: Welsh LC]]
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[[Category: Single protein]]
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[[Category: Yu M]]
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[[Category: Thermus phage ph75]]
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[[Category: Marvin, D A.]]
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[[Category: Pederson, D M.]]
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[[Category: Perham, R N.]]
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[[Category: Sampson, M.]]
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[[Category: Slater, M R.]]
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[[Category: Welsh, L C.]]
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[[Category: Yu, M.]]
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[[Category: Filamentous bacteriophage]]
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[[Category: Helical virus]]
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[[Category: Helical virus coat protein]]
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[[Category: Inovirus]]
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[[Category: Membrane protein]]
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[[Category: Ssdna viruse]]
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[[Category: Thermophile]]
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[[Category: Virus coat protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:50:18 2008''
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Current revision

Filamentous Bacteriophage PH75

PDB ID 1hh0

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