3s47

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Current revision (09:47, 1 March 2024) (edit) (undo)
 
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<StructureSection load='3s47' size='340' side='right'caption='[[3s47]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3s47' size='340' side='right'caption='[[3s47]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3s47]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clob8 Clob8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S47 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3s47]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Clostridium_beijerinckii_NCIMB_8052 Clostridium beijerinckii NCIMB 8052]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S47 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S47 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3gy1|3gy1]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Cbei_4837 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=290402 CLOB8])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s47 OCA], [https://pdbe.org/3s47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s47 RCSB], [https://www.ebi.ac.uk/pdbsum/3s47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s47 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s47 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s47 OCA], [https://pdbe.org/3s47 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s47 RCSB], [https://www.ebi.ac.uk/pdbsum/3s47 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s47 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/IMAND_CLOB8 IMAND_CLOB8]] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref>
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[https://www.uniprot.org/uniprot/IMAND_CLOB8 IMAND_CLOB8] Has no detectable activity with D-mannonate and with a panel of 70 other acid sugars (in vitro), in spite of the conservation of the residues that are expected to be important for catalytic activity and cofactor binding. May have evolved a divergent function.<ref>PMID:24697546</ref>
==See Also==
==See Also==
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*[[Enolase 3D structures|Enolase 3D structures]]
*[[Mandelate racemase|Mandelate racemase]]
*[[Mandelate racemase|Mandelate racemase]]
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
*[[Mandelate racemase/muconate lactonizing enzyme 3D structures|Mandelate racemase/muconate lactonizing enzyme 3D structures]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Clob8]]
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[[Category: Clostridium beijerinckii NCIMB 8052]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Almo, S C]]
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[[Category: Almo SC]]
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[[Category: Fedorov, A A]]
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[[Category: Fedorov AA]]
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[[Category: Fedorov, E V]]
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[[Category: Fedorov EV]]
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[[Category: Gerlt, J A]]
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[[Category: Gerlt JA]]
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[[Category: Wichelecki, D]]
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[[Category: Wichelecki D]]
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[[Category: Acid sugar]]
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[[Category: Dehydratase]]
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[[Category: Enolase fold]]
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[[Category: Isomerase]]
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Current revision

Crystal structure of enolase superfamily member from Clostridium beijerincki complexed with Mg

PDB ID 3s47

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