3s6i
From Proteopedia
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<StructureSection load='3s6i' size='340' side='right'caption='[[3s6i]], [[Resolution|resolution]] 2.28Å' scene=''> | <StructureSection load='3s6i' size='340' side='right'caption='[[3s6i]], [[Resolution|resolution]] 2.28Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3s6i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3s6i]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3S6I OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3S6I FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.28Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3DR:1,2-DIDEOXYRIBOFURANOSE-5-PHOSPHATE'>3DR</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s6i OCA], [https://pdbe.org/3s6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s6i RCSB], [https://www.ebi.ac.uk/pdbsum/3s6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s6i ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3s6i FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3s6i OCA], [https://pdbe.org/3s6i PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3s6i RCSB], [https://www.ebi.ac.uk/pdbsum/3s6i PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3s6i ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
- | + | [https://www.uniprot.org/uniprot/MAG1_SCHPO MAG1_SCHPO] Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine or 7-methyladenine from the damaged DNA polymer formed by alkylation lesions. Can release ethylated and propylated bases from DNA in addition to 3-methyladenine. | |
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==See Also== | ==See Also== | ||
*[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] | *[[DNA glycosylase 3D structures|DNA glycosylase 3D structures]] | ||
- | == References == | ||
- | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: DNA-3-methyladenine glycosylase II]] | ||
- | [[Category: Fission yeast]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: | + | [[Category: Schizosaccharomyces pombe 972h-]] |
- | [[Category: | + | [[Category: Adhikary S]] |
- | [[Category: | + | [[Category: Eichman BF]] |
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Current revision
Schizosaccaromyces pombe 3-methyladenine DNA glycosylase (Mag1) in complex with abasic-DNA.
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