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7xwy
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of spFft3 N-terminal truncation== | |
| - | + | <StructureSection load='7xwy' size='340' side='right'caption='[[7xwy]], [[Resolution|resolution]] 2.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7xwy]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XWY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XWY FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.25Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xwy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xwy OCA], [https://pdbe.org/7xwy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xwy RCSB], [https://www.ebi.ac.uk/pdbsum/7xwy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xwy ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FFT3_SCHPO FFT3_SCHPO] DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling activity and is required for heterochromatin organization. Required for maintaining a heterochromatin chromatin structure at centromeres and subtelomeres by protecting these regions from euchromatin assembly. Enhances the nucleotide exchange activity of the pim1 guanine nucleotide exchange factor and abolishes histone-H3-mediated RanGAP inhibition. Involved in the construction of the centromeres.<ref>PMID:15317843</ref> <ref>PMID:18422602</ref> <ref>PMID:21437270</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Schizosaccharomyces pombe 972h-]] | ||
| + | [[Category: Huo Y]] | ||
| + | [[Category: Jiang T]] | ||
| + | [[Category: Zhang N]] | ||
Current revision
Crystal structure of spFft3 N-terminal truncation
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