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8cz9
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal Structure of the E372K LNK SH2 Domain mutant in Complex with a JAK2 pY813 Phosphopeptide== | |
| - | + | <StructureSection load='8cz9' size='340' side='right'caption='[[8cz9]], [[Resolution|resolution]] 1.65Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8cz9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZ9 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=PTR:O-PHOSPHOTYROSINE'>PTR</scene></td></tr> |
| - | [[Category: Babon | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8cz9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8cz9 OCA], [https://pdbe.org/8cz9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8cz9 RCSB], [https://www.ebi.ac.uk/pdbsum/8cz9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8cz9 ProSAT]</span></td></tr> |
| - | [[Category: Kershaw | + | </table> |
| - | [[Category: Morris | + | == Function == |
| + | [https://www.uniprot.org/uniprot/SH2B3_RAT SH2B3_RAT] Links T-cell receptor activation signal to phospholipase C-gamma-1, GRB2 and phosphatidylinositol 3-kinase. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Babon JJ]] | ||
| + | [[Category: Kershaw NJ]] | ||
| + | [[Category: Morris R]] | ||
Current revision
Crystal Structure of the E372K LNK SH2 Domain mutant in Complex with a JAK2 pY813 Phosphopeptide
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