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7tth
From Proteopedia
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| - | == | + | ==Human potassium-chloride cotransporter 1 in inward-open state== |
| - | <StructureSection load='7tth' size='340' side='right'caption='[[7tth]]' scene=''> | + | <StructureSection load='7tth' size='340' side='right'caption='[[7tth]], [[Resolution|resolution]] 3.25Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TTH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7tth]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TTH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TTH FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tth OCA], [https://pdbe.org/7tth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tth RCSB], [https://www.ebi.ac.uk/pdbsum/7tth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tth ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tth FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tth OCA], [https://pdbe.org/7tth PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tth RCSB], [https://www.ebi.ac.uk/pdbsum/7tth PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tth ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/S12A4_HUMAN S12A4_HUMAN]] Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May contribute to cell volume homeostasis in single cells. May be involved in the regulation of basolateral Cl(-) exit in NaCl absorbing epithelia (By similarity). Isoform 4 has no transport activity. | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Cao EH]] |
| + | [[Category: Zhao YX]] | ||
Current revision
Human potassium-chloride cotransporter 1 in inward-open state
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