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7xmu
From Proteopedia
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==E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P== | ==E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P== | ||
| - | <StructureSection load='7xmu' size='340' side='right'caption='[[7xmu]]' scene=''> | + | <StructureSection load='7xmu' size='340' side='right'caption='[[7xmu]], [[Resolution|resolution]] 2.30Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XMU FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7xmu]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._MG1655 Escherichia coli str. K-12 substr. MG1655]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XMU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XMU FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xmu OCA], [https://pdbe.org/7xmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xmu RCSB], [https://www.ebi.ac.uk/pdbsum/7xmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xmu ProSAT]</span></td></tr> | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=HSX:5-O-PHOSPHONO-ALPHA-D-RIBOFURANOSE'>HSX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xmu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xmu OCA], [https://pdbe.org/7xmu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xmu RCSB], [https://www.ebi.ac.uk/pdbsum/7xmu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xmu ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [[https://www.uniprot.org/uniprot/KPRS_ECOLI KPRS_ECOLI]] Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib-5-P).[HAMAP-Rule:MF_00583]<ref>PMID:10954724</ref> <ref>PMID:2542328</ref> <ref>PMID:3009477</ref> <ref>PMID:6290219</ref> <ref>PMID:7657655</ref> <ref>PMID:8679571</ref> <ref>PMID:9125530</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Escherichia coli str. K-12 substr. MG1655]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Hu | + | [[Category: Chang CC]] |
| + | [[Category: Hu HH]] | ||
| + | [[Category: Liu JL]] | ||
| + | [[Category: Lu GM]] | ||
Current revision
E.coli phosphoribosylpyrophosphate (PRPP) synthetase type A filament bound with ADP, Pi and R5P
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