3ssb

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (13:06, 14 March 2024) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3ssb' size='340' side='right'caption='[[3ssb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='3ssb' size='340' side='right'caption='[[3ssb]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3ssb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] and [https://en.wikipedia.org/wiki/Galme Galme]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSB FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3ssb]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus] and [https://en.wikipedia.org/wiki/Galleria_mellonella Galleria mellonella]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3SSB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3SSB FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">IMPI ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7137 GALME])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssb OCA], [https://pdbe.org/3ssb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssb RCSB], [https://www.ebi.ac.uk/pdbsum/3ssb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3ssb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3ssb OCA], [https://pdbe.org/3ssb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3ssb RCSB], [https://www.ebi.ac.uk/pdbsum/3ssb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3ssb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease. [[https://www.uniprot.org/uniprot/IMPI_GALME IMPI_GALME]] Inhibits thermolysin, bacillolysin and pseudolysin, B.polymyxa metalloprotease and human MMP1 and MMP3. No activity on trypsin or cysteine protease papain.<ref>PMID:15115439</ref> <ref>PMID:9738891</ref>
+
[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
==See Also==
==See Also==
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
*[[Thermolysin 3D structures|Thermolysin 3D structures]]
-
== References ==
 
-
<references/>
 
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Bacillus thermoproteolyticus]]
[[Category: Bacillus thermoproteolyticus]]
-
[[Category: Galme]]
+
[[Category: Galleria mellonella]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Thermolysin]]
+
[[Category: Arolas JL]]
-
[[Category: Arolas, J L]]
+
[[Category: Botelho TO]]
-
[[Category: Botelho, T O]]
+
[[Category: Gomis-Ruth FX]]
-
[[Category: Gomis-Ruth, F X]]
+
[[Category: Vilcinskas A]]
-
[[Category: Vilcinskas, A]]
+
-
[[Category: Hydrolase-hydrolase inhibitor complex]]
+
-
[[Category: Metalloprotease thermolysin inhibitor]]
+
-
[[Category: Secreted]]
+
-
[[Category: Thermolysin fold - family i8 fold]]
+
-
[[Category: Zn binding]]
+

Current revision

Structure of Insect Metalloproteinase Inhibitor in Complex with Thermolysin

PDB ID 3ssb

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools