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| - | [[Image:1hkz.gif|left|200px]]
| + | REMOVED: The PDB entry 1hkz was removed. |
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| - | {{STRUCTURE_1hkz| PDB=1hkz | SCENE= }}
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| - | '''CRYSTAL STRUCTURE OF BACILLUS SUBTILIS COTA AFTER 8H SOAKING WITH ABTS'''
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| - | ==Overview==
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| - | The CotA laccase from the endospore coat of Bacillus subtilis has been crystallized in the presence of the non-catalytic co-oxidant 2,2'-azinobis-(3-ethylbenzothiazoline-6-sulfonate) (ABTS), and the structure was determined using synchrotron radiation. The binding site for this adduct is well defined and indicates how ABTS, in conjunction with laccases, could act as an oxidative mediator toward non-phenolic moieties. In addition, a dioxygen moiety is clearly defined within the solvent channel oriented toward one of the T3 copper atoms in the trinuclear center.
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| - | ==About this Structure==
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| - | 1HKZ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HKZ OCA].
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| - | ==Reference==
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| - | Substrate and dioxygen binding to the endospore coat laccase from Bacillus subtilis., Enguita FJ, Marcal D, Martins LO, Grenha R, Henriques AO, Lindley PF, Carrondo MA, J Biol Chem. 2004 May 28;279(22):23472-6. Epub 2004 Feb 4. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/14764581 14764581]
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| - | [[Category: Bacillus subtilis]]
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| - | [[Category: Single protein]]
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| - | [[Category: Carrondo, M A.]]
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| - | [[Category: Enguita, F J.]]
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| - | [[Category: Grenha, R.]]
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| - | [[Category: Henriques, A O.]]
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| - | [[Category: Marcal, D.]]
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| - | [[Category: Martins, L O.]]
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| - | [[Category: Endospore coat]]
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| - | [[Category: Laccase]]
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| - | [[Category: Oxidase,copper-binding]]
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| - | [[Category: Reaction cycle,sporulation]]
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| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 18:57:54 2008''
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