8a1g

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:24, 19 June 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8a1g is ON HOLD until Paper Publication
+
==Structure of the SNX1-SNX5 complex==
 +
<StructureSection load='8a1g' size='340' side='right'caption='[[8a1g]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[8a1g]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A1G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A1G FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=POL:N-PROPANOL'>POL</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a1g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a1g OCA], [https://pdbe.org/8a1g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a1g RCSB], [https://www.ebi.ac.uk/pdbsum/8a1g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a1g ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/SNX1_HUMAN SNX1_HUMAN] May be involved in several stages of intracellular trafficking. Plays a role in targeting ligand-activated EGFR to the lysosomes for degradation after endocytosis from the cell surface and release from the Golgi. Component of the retromer complex, a complex required to retrieve lysosomal enzyme receptors (IGF2R and M6PR) from endosomes to the trans-Golgi network. Interacts with membranes containing phosphatidylinositol 3-phosphate (PtdIns(3P)) or phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2).<ref>PMID:12198132</ref> <ref>PMID:15498486</ref> <ref>PMID:17101778</ref>
-
Authors: Lopez, C., Scaramuzza, S., Astorga-Simon, E.N., Banos-Mateos, S., Vidaurrazaga, A., Rojas, A.L., Castano, D., Hierro, A.
+
==See Also==
-
 
+
*[[Sorting nexin 3D structures|Sorting nexin 3D structures]]
-
Description: SNXs
+
== References ==
-
[[Category: Unreleased Structures]]
+
<references/>
-
[[Category: Castano, D]]
+
__TOC__
-
[[Category: Banos-Mateos, S]]
+
</StructureSection>
-
[[Category: Hierro, A]]
+
[[Category: Homo sapiens]]
-
[[Category: Astorga-Simon, E.N]]
+
[[Category: Large Structures]]
-
[[Category: Scaramuzza, S]]
+
[[Category: Astorga-Simon EN]]
-
[[Category: Vidaurrazaga, A]]
+
[[Category: Banos-Mateos S]]
-
[[Category: Rojas, A.L]]
+
[[Category: Castano D]]
-
[[Category: Lopez, C]]
+
[[Category: Hierro A]]
 +
[[Category: Lopez-Robles C]]
 +
[[Category: Rojas AL]]
 +
[[Category: Scaramuzza S]]
 +
[[Category: Vidaurrazaga A]]

Current revision

Structure of the SNX1-SNX5 complex

PDB ID 8a1g

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8a1g"
Personal tools