7f9u
From Proteopedia
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==Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor T35 and Halofuginone== | ==Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor T35 and Halofuginone== | ||
| - | <StructureSection load='7f9u' size='340' side='right'caption='[[7f9u]]' scene=''> | + | <StructureSection load='7f9u' size='340' side='right'caption='[[7f9u]], [[Resolution|resolution]] 2.80Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F9U FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7f9u]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7F9U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7F9U FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f9u OCA], [https://pdbe.org/7f9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f9u RCSB], [https://www.ebi.ac.uk/pdbsum/7f9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f9u ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1TI:4-[(3S)-3-cyano-3-(1-methylcyclopropyl)-2-oxidanylidene-pyrrolidin-1-yl]-N-[[3-fluoranyl-5-(1-methylpyrazol-4-yl)phenyl]methyl]-6-methyl-pyridine-2-carboxamide'>1TI</scene>, <scene name='pdbligand=BR:BROMIDE+ION'>BR</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=HFG:7-BROMO-6-CHLORO-3-{3-[(2R,3S)-3-HYDROXYPIPERIDIN-2-YL]-2-OXOPROPYL}QUINAZOLIN-4(3H)-ONE'>HFG</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7f9u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7f9u OCA], [https://pdbe.org/7f9u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7f9u RCSB], [https://www.ebi.ac.uk/pdbsum/7f9u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7f9u ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A7J6JUK2_TOXGO A0A7J6JUK2_TOXGO] | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Aminoacyl tRNA synthetase 3D structures|Aminoacyl tRNA synthetase 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Toxoplasma gondii]] | ||
[[Category: Malhotra N]] | [[Category: Malhotra N]] | ||
[[Category: Manickam Y]] | [[Category: Manickam Y]] | ||
[[Category: Sharma A]] | [[Category: Sharma A]] | ||
Current revision
Toxoplasma gondii Prolyl-tRNA Synthetase (TgPRS) in Complex with inhibitor T35 and Halofuginone
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