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7tvh
From Proteopedia
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==Hyperlytic variant of Tae1, Type VI secretion amidase effector 1, from Pseudomonas aeruginosa (Cys110Ser)== | ==Hyperlytic variant of Tae1, Type VI secretion amidase effector 1, from Pseudomonas aeruginosa (Cys110Ser)== | ||
| - | <StructureSection load='7tvh' size='340' side='right'caption='[[7tvh]]' scene=''> | + | <StructureSection load='7tvh' size='340' side='right'caption='[[7tvh]], [[Resolution|resolution]] 1.71Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TVH FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[7tvh]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7TVH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7TVH FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tvh OCA], [https://pdbe.org/7tvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tvh RCSB], [https://www.ebi.ac.uk/pdbsum/7tvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tvh ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71Å</td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7tvh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7tvh OCA], [https://pdbe.org/7tvh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7tvh RCSB], [https://www.ebi.ac.uk/pdbsum/7tvh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7tvh ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/TSE1_PSEAE TSE1_PSEAE] Toxin secreted by the H1 type VI (H1-T6SS) secretion system into the periplasm of recipient cells. Degrades peptidoglycan via amidase activity thereby helping itself to compete with other bacteria (PubMed:21776080, PubMed:22931054, PubMed:22813741, PubMed:22700987). To protect itself, the bacterium synthesizes immunity protein Tsi1 that specifically interacts with and inactivates cognate toxin (PubMed:21776080, PubMed:22931054, PubMed:22700987).<ref>PMID:21776080</ref> <ref>PMID:22700987</ref> <ref>PMID:22813741</ref> <ref>PMID:22931054</ref> | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa PAO1]] | ||
[[Category: Chou S]] | [[Category: Chou S]] | ||
[[Category: Radkov A]] | [[Category: Radkov A]] | ||
[[Category: Saunders H]] | [[Category: Saunders H]] | ||
Current revision
Hyperlytic variant of Tae1, Type VI secretion amidase effector 1, from Pseudomonas aeruginosa (Cys110Ser)
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