7ycx

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m (Protected "7ycx" [edit=sysop:move=sysop])
Current revision (10:06, 27 September 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 7ycx is ON HOLD
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==The structure of INTAC-PEC complex==
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<StructureSection load='7ycx' size='340' side='right'caption='[[7ycx]], [[Resolution|resolution]] 4.18&Aring;' scene=''>
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Authors: Zheng, H., Jin, Q., Wang, X., Qi, Y., Liu, W., Ren, Y., Zhao, D., Chen, F.X., Cheng, J., Chen, X., Xu, Y.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7ycx]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YCX FirstGlance]. <br>
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Description: The structure of INTAC-PEC complex
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.18&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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[[Category: Cheng, J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ycx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ycx OCA], [https://pdbe.org/7ycx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ycx RCSB], [https://www.ebi.ac.uk/pdbsum/7ycx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ycx ProSAT]</span></td></tr>
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[[Category: Zheng, H]]
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</table>
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[[Category: Chen, F.X]]
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== Disease ==
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[[Category: Chen, X]]
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[https://www.uniprot.org/uniprot/INT1_HUMAN INT1_HUMAN] The disease is caused by variants affecting the gene represented in this entry.
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[[Category: Liu, W]]
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== Function ==
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[[Category: Ren, Y]]
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[https://www.uniprot.org/uniprot/INT1_HUMAN INT1_HUMAN] Component of the Integrator (INT) complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes (Probable). Mediates recruitment of cytoplasmic dynein to the nuclear envelope, probably as component of the INT complex (PubMed:23904267).<ref>PMID:23904267</ref> <ref>PMID:16239144</ref>
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[[Category: Jin, Q]]
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== References ==
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[[Category: Qi, Y]]
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<references/>
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[[Category: Wang, X]]
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__TOC__
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[[Category: Xu, Y]]
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</StructureSection>
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[[Category: Zhao, D]]
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Chen FX]]
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[[Category: Chen X]]
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[[Category: Cheng J]]
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[[Category: Jin Q]]
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[[Category: Liu W]]
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[[Category: Qi Y]]
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[[Category: Ren Y]]
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[[Category: Wang X]]
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[[Category: Xu Y]]
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[[Category: Zhao D]]
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[[Category: Zheng H]]

Current revision

The structure of INTAC-PEC complex

PDB ID 7ycx

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OCA

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