This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8d1h
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
==hBest2 Ca2+-unbound closed state== | ==hBest2 Ca2+-unbound closed state== | ||
| - | <StructureSection load='8d1h' size='340' side='right'caption='[[8d1h]]' scene=''> | + | <StructureSection load='8d1h' size='340' side='right'caption='[[8d1h]], [[Resolution|resolution]] 1.94Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D1H FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[8d1h]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8D1H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8D1H FirstGlance]. <br> |
| - | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d1h OCA], [https://pdbe.org/8d1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d1h RCSB], [https://www.ebi.ac.uk/pdbsum/8d1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d1h ProSAT]</span></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 1.94Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DU0:2-[2-[(1~{S},2~{S},4~{S},5~{R},6~{R},7~{S},8~{R},9~{S},12~{S},13~{R},16~{S})-5,7,9,13-tetramethylspiro[5-oxapentacyclo[10.8.0.0^{2,9}.0^{4,8}.0^{13,18}]icos-18-ene-6,2-oxane]-16-yl]oxyethyl]propane-1,3-diol'>DU0</scene>, <scene name='pdbligand=MC3:1,2-DIMYRISTOYL-RAC-GLYCERO-3-PHOSPHOCHOLINE'>MC3</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8d1h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8d1h OCA], [https://pdbe.org/8d1h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8d1h RCSB], [https://www.ebi.ac.uk/pdbsum/8d1h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8d1h ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BEST2_HUMAN BEST2_HUMAN] Forms calcium-sensitive chloride channels. Permeable to bicarbonate.<ref>PMID:11904445</ref> <ref>PMID:12907679</ref> <ref>PMID:18400985</ref> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Bestrophin 3D structures|Bestrophin 3D structures]] | ||
| + | == References == | ||
| + | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Hendrickson WA]] | [[Category: Hendrickson WA]] | ||
Current revision
hBest2 Ca2+-unbound closed state
| |||||||||||
