7p2m

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==E.coli GyrB24 with inhibitor LMD43 (EBL2560)==
==E.coli GyrB24 with inhibitor LMD43 (EBL2560)==
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<StructureSection load='7p2m' size='340' side='right'caption='[[7p2m]]' scene=''>
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<StructureSection load='7p2m' size='340' side='right'caption='[[7p2m]], [[Resolution|resolution]] 1.16&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[7p2m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7P2M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7P2M FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2m OCA], [https://pdbe.org/7p2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2m RCSB], [https://www.ebi.ac.uk/pdbsum/7p2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2m ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.16&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=N1N:2-[[3,4-bis(chloranyl)-5-methyl-1~{H}-pyrrol-2-yl]carbonylamino]-4-phenylmethoxy-1,3-benzothiazole-6-carboxylic+acid'>N1N</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7p2m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7p2m OCA], [https://pdbe.org/7p2m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7p2m RCSB], [https://www.ebi.ac.uk/pdbsum/7p2m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7p2m ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GYRB_ECOLI GYRB_ECOLI] DNA gyrase negatively supercoils closed circular double-stranded DNA in an ATP-dependent manner and also catalyzes the interconversion of other topological isomers of double-stranded DNA rings, including catenanes and knotted rings.<ref>PMID:12051843</ref> <ref>PMID:18642932</ref> <ref>PMID:20675723</ref>
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==See Also==
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*[[Gyrase 3D Structures|Gyrase 3D Structures]]
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== References ==
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<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Escherichia coli K-12]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Durcik M]]
[[Category: Durcik M]]

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E.coli GyrB24 with inhibitor LMD43 (EBL2560)

PDB ID 7p2m

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