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3vjj

From Proteopedia

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Current revision (08:40, 20 March 2024) (edit) (undo)
 
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<StructureSection load='3vjj' size='340' side='right'caption='[[3vjj]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
<StructureSection load='3vjj' size='340' side='right'caption='[[3vjj]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3vjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rbsdv Rbsdv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VJJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3vjj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rice_black_streaked_dwarf_virus Rice black streaked dwarf virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VJJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VJJ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vjj OCA], [https://pdbe.org/3vjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vjj RCSB], [https://www.ebi.ac.uk/pdbsum/3vjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vjj ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vjj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vjj OCA], [https://pdbe.org/3vjj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vjj RCSB], [https://www.ebi.ac.uk/pdbsum/3vjj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vjj ProSAT]</span></td></tr>
</table>
</table>
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<div style="background-color:#fffaf0;">
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== Function ==
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== Publication Abstract from PubMed ==
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[https://www.uniprot.org/uniprot/Q913E4_RBSDV Q913E4_RBSDV]
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The P9-1 protein of Rice black streaked dwarf virus accumulates in viroplasm inclusions, which are structures that appear to play an important role in viral morphogenesis and are commonly found in viruses in the family Reoviridae. Crystallographic analysis of P9-1 revealed structural features that allow the protein to form dimers via hydrophobic interactions. Each dimer had carboxy-terminal regions, resembling arms, that extended to neighboring dimers, thereby uniting sets of four dimers via lateral hydrophobic interactions to yield cylindrical octamers. The importance of these regions for the formation of viroplasm-like inclusions was confirmed by the absence of such inclusions when P9-1 was expressed without its carboxy-terminal arm. The octamers were vertically elongated cylinders, resembling the structures formed by NSP2 of rotavirus, even though there were no significant similarities between the respective primary and secondary structures of the two proteins. Our results suggest that an octameric structure with an internal pore might be important for the functioning of the respective proteins in the events that occur in the viroplasm, which might include viral morphogenesis.
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Crystallographic Analysis Reveals Octamerization of Viroplasm Matrix Protein P9-1 of Rice Black Streaked Dwarf Virus.,Akita F, Higashiura A, Shimizu T, Pu Y, Suzuki M, Uehara-Ichiki T, Sasaya T, Kanamaru S, Arisaka F, Tsukihara T, Nakagawa A, Omura T J Virol. 2011 Nov 9. PMID:22072761<ref>PMID:22072761</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3vjj" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Rbsdv]]
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[[Category: Rice black streaked dwarf virus]]
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[[Category: Akita, F]]
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[[Category: Akita F]]
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[[Category: Higashiura, A]]
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[[Category: Higashiura A]]
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[[Category: Nakagawa, A]]
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[[Category: Nakagawa A]]
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[[Category: Omura, T]]
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[[Category: Omura T]]
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[[Category: Suzuki, M]]
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[[Category: Suzuki M]]
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[[Category: Tsukihara, T]]
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[[Category: Tsukihara T]]
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[[Category: Viral protein]]
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[[Category: Viroplasm]]
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Current revision

Crystal Structure Analysis of the P9-1

PDB ID 3vjj

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