This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


3vyn

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (12:42, 8 November 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='3vyn' size='340' side='right'caption='[[3vyn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
<StructureSection load='3vyn' size='340' side='right'caption='[[3vyn]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[3vyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VYN FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[3vyn]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3VYN OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3VYN FirstGlance]. <br>
-
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[3vyo|3vyo]], [[3vyp|3vyp]]</div></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Rv2518c ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1773 "Bacillus tuberculosis" (Zopf 1883) Klein 1884])</td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Peptidyltransferase Peptidyltransferase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.2.12 2.3.2.12] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vyn OCA], [https://pdbe.org/3vyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vyn RCSB], [https://www.ebi.ac.uk/pdbsum/3vyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vyn ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3vyn FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3vyn OCA], [https://pdbe.org/3vyn PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3vyn RCSB], [https://www.ebi.ac.uk/pdbsum/3vyn PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3vyn ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/LDT2_MYCTU LDT2_MYCTU] Generates 3->3 cross-links in peptidoglycan, catalyzing the cleavage of the mDap(3)-D-Ala(4) bond of a tetrapeptide donor stem and the formation of a bond between the carbonyl of mDap(3) of the donor stem and the side chain of mDap(3) of the acceptor stem. Is specific for donor substrates containing a stem tetrapeptide since it cannot use pentapeptide stems.<ref>PMID:24041897</ref>
 +
== References ==
 +
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Peptidyltransferase]]
+
[[Category: Mycobacterium tuberculosis]]
-
[[Category: Bi, L J]]
+
[[Category: Bi LJ]]
-
[[Category: Li, D F]]
+
[[Category: Li DF]]
-
[[Category: Li, W J]]
+
[[Category: Li WJ]]
-
[[Category: Wang, D C]]
+
[[Category: Wang DC]]
-
[[Category: Beta barrel]]
+
-
[[Category: Beta-lactam binding]]
+
-
[[Category: D-transpeptidase]]
+
-
[[Category: Transferase]]
+
-
[[Category: Ykud domain]]
+

Current revision

Crystal structure of Mycobacterium tuberculosis L,D-transpeptidase LdtMt2 N55 truncation mutant (resideus 55-408)

PDB ID 3vyn

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools