8a4d

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'''Unreleased structure'''
 
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The entry 8a4d is ON HOLD until Paper Publication
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==1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with thiamine analog inhibitor==
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<StructureSection load='8a4d' size='340' side='right'caption='[[8a4d]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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Authors: Hamid, R., Hirsch, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8a4d]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_LESB58 Pseudomonas aeruginosa LESB58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A4D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A4D FirstGlance]. <br>
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Description: 1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with thiamine analog inhibitor
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=26G:2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]PHENYL}ETHANOL'>26G</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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[[Category: Hamid, R]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a4d OCA], [https://pdbe.org/8a4d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a4d RCSB], [https://www.ebi.ac.uk/pdbsum/8a4d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a4d ProSAT]</span></td></tr>
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[[Category: Hirsch, A]]
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DXS_PSEA8 DXS_PSEA8] Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP).
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa LESB58]]
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[[Category: Hamid R]]
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[[Category: Hirsch A]]

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1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with thiamine analog inhibitor

PDB ID 8a4d

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