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8czt
From Proteopedia
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<StructureSection load='8czt' size='340' side='right'caption='[[8czt]], [[Resolution|resolution]] 2.10Å' scene=''> | <StructureSection load='8czt' size='340' side='right'caption='[[8czt]], [[Resolution|resolution]] 2.10Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[8czt]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZT FirstGlance]. <br> | + | <table><tr><td colspan='2'>[[8czt]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Middle_East_respiratory_syndrome-related_coronavirus Middle East respiratory syndrome-related coronavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8CZT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8CZT FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P8L:[(1~{S},2~{R})-2-cyclohexylcyclopropyl]methyl+~{N}-[(2~{S})-1-[[(1~{R},2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P8L</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> |
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P8L:[(1~{S},2~{R})-2-cyclohexylcyclopropyl]methyl+~{N}-[(2~{S})-1-[[(1~{R},2~{S})-1-[bis(oxidanyl)-oxidanylidene-$l^{5}-sulfanyl]-1-oxidanyl-3-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]propan-2-yl]amino]-4-methyl-1-oxidanylidene-pentan-2-yl]carbamate'>P8L</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czt OCA], [https://pdbe.org/8czt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czt RCSB], [https://www.ebi.ac.uk/pdbsum/8czt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czt ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8czt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8czt OCA], [https://pdbe.org/8czt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8czt RCSB], [https://www.ebi.ac.uk/pdbsum/8czt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8czt ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A1L2E0X0_MERS A0A1L2E0X0_MERS] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Battaile | + | [[Category: Middle East respiratory syndrome-related coronavirus]] |
| - | [[Category: Chamandi | + | [[Category: Battaile KP]] |
| - | [[Category: Chang | + | [[Category: Chamandi SD]] |
| - | [[Category: Groutas | + | [[Category: Chang KO]] |
| - | [[Category: Kim | + | [[Category: Groutas WC]] |
| - | [[Category: Liu | + | [[Category: Kim Y]] |
| - | [[Category: Lovell | + | [[Category: Liu L]] |
| - | [[Category: Madden | + | [[Category: Lovell S]] |
| - | [[Category: Nguyen | + | [[Category: Madden TK]] |
| - | [[Category: Picard | + | [[Category: Nguyen HN]] |
| - | [[Category: Thruman | + | [[Category: Picard HR]] |
| - | + | [[Category: Thruman HA]] | |
| - | + | ||
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Current revision
Structure of MERS 3CL protease in complex with the cyclopropane based inhibitor 15d
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