3w9f
From Proteopedia
(Difference between revisions)
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<StructureSection load='3w9f' size='340' side='right'caption='[[3w9f]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='3w9f' size='340' side='right'caption='[[3w9f]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
- | <table><tr><td colspan='2'>[[3w9f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[3w9f]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3W9F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3W9F FirstGlance]. <br> |
- | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
- | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I3P:D-MYO-INOSITOL-1,4,5-TRIPHOSPHATE'>I3P</scene></td></tr> |
- | + | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w9f OCA], [https://pdbe.org/3w9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w9f RCSB], [https://www.ebi.ac.uk/pdbsum/3w9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w9f ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3w9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3w9f OCA], [https://pdbe.org/3w9f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3w9f RCSB], [https://www.ebi.ac.uk/pdbsum/3w9f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3w9f ProSAT]</span></td></tr> | ||
</table> | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/TRPV4_CHICK TRPV4_CHICK] Non-selective calcium permeant cation channel involved in osmotic sensitivity and mechanosensitivity (PubMed:11081638). Activation by exposure to hypotonicity within the physiological range exhibits an outward rectification (PubMed:11081638). Also activated by phorbol esters (PubMed:19864432). Channel activity seems to be regulated by a calmodulin-dependent mechanism (By similarity).[UniProtKB:Q9HBA0]<ref>PMID:11081638</ref> <ref>PMID:19864432</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
- | [[Category: | + | [[Category: Gallus gallus]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
- | [[Category: Hamada-nakahara | + | [[Category: Hamada-nakahara S]] |
- | [[Category: Itoh | + | [[Category: Itoh Y]] |
- | [[Category: Suetsugu | + | [[Category: Suetsugu S]] |
- | + | ||
- | + | ||
- | + |
Current revision
Crystal structure of the ankyrin repeat domain of chicken TRPV4 in complex with IP3
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