3wj9

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<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
<StructureSection load='3wj9' size='340' side='right'caption='[[3wj9]], [[Resolution|resolution]] 2.51&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Fission_yeast Fission yeast]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3wj9]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe_972h- Schizosaccharomyces pombe 972h-]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3WJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3WJ9 FirstGlance]. <br>
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</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.506&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">SPBC4B4.04 ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284812 Fission yeast])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3wj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3wj9 OCA], [https://pdbe.org/3wj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3wj9 RCSB], [https://www.ebi.ac.uk/pdbsum/3wj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3wj9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO]] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).
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[https://www.uniprot.org/uniprot/EIF2A_SCHPO EIF2A_SCHPO] Functions in the early steps of protein synthesis of a small number of specific mRNAs. Acts by directing the binding of methionyl-tRNAi to 40S ribosomal subunits. In contrast to the eIF-2 complex, it binds methionyl-tRNAi to 40 S subunits in a codon-dependent manner, whereas the eIF-2 complex binds methionyl-tRNAi to 40 S subunits in a GTP-dependent manner. May act by impiging the expression of specific proteins (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Fission yeast]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ito, T]]
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[[Category: Schizosaccharomyces pombe 972h-]]
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[[Category: Kashiwagi, K]]
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[[Category: Ito T]]
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[[Category: Yokoyama, S]]
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[[Category: Kashiwagi K]]
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[[Category: Beta-propeller]]
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[[Category: Yokoyama S]]
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[[Category: Translation]]
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Current revision

Crystal structure of the eukaryotic initiation factor

PDB ID 3wj9

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