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8akm
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8akm is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Acyl-enzyme complex of ertapenem bound to deacylation mutant KPC-2 (E166Q)== | |
| - | + | <StructureSection load='8akm' size='340' side='right'caption='[[8akm]], [[Resolution|resolution]] 1.25Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8akm]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Klebsiella_pneumoniae Klebsiella pneumoniae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AKM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AKM FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.25Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=N9X:Ertapenem'>N9X</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8akm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8akm OCA], [https://pdbe.org/8akm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8akm RCSB], [https://www.ebi.ac.uk/pdbsum/8akm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8akm ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/BLKPC_KLEPN BLKPC_KLEPN] Hydrolyzes carbapenems, penicillins, cephalosporins and monobactams with varying efficiency. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Klebsiella pneumoniae]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Hinchliffe P]] | ||
| + | [[Category: Spencer J]] | ||
| + | [[Category: Tooke CL]] | ||
Current revision
Acyl-enzyme complex of ertapenem bound to deacylation mutant KPC-2 (E166Q)
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