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8dv6

From Proteopedia

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Current revision (06:21, 19 July 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8dv6 is ON HOLD until Paper Publication
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==Zika virus envelope protein structure in complex with a potent Human mAb==
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<StructureSection load='8dv6' size='340' side='right'caption='[[8dv6]], [[Resolution|resolution]] 3.38&Aring;' scene=''>
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Authors: Cameron, A., Puhl, A.C., deSilva, A.M., Premkumar, L.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8dv6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Zika_virus_ZIKV/Human/Cambodia/FSS13025/2010 Zika virus ZIKV/Human/Cambodia/FSS13025/2010]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DV6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DV6 FirstGlance]. <br>
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Description: Zika virus envelope protein structure in complex with a potent Human mAb
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.38&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dv6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dv6 OCA], [https://pdbe.org/8dv6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dv6 RCSB], [https://www.ebi.ac.uk/pdbsum/8dv6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dv6 ProSAT]</span></td></tr>
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[[Category: Cameron, A]]
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</table>
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[[Category: Premkumar, L]]
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== Function ==
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[[Category: Puhl, A.C]]
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[https://www.uniprot.org/uniprot/A0A384KMW4_ZIKV A0A384KMW4_ZIKV] Functions as a signal peptide for NS4B and is required for the interferon antagonism activity of the latter.[ARBA:ARBA00003504] Serine protease subunit NS2B: Required cofactor for the serine protease function of NS3.[PROSITE-ProRule:PRU00859]
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[[Category: Desilva, A.M]]
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Zika virus ZIKV/Human/Cambodia/FSS13025/2010]]
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[[Category: Cameron A]]
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[[Category: Premkumar L]]
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[[Category: Puhl AC]]
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[[Category: DeSilva AM]]

Current revision

Zika virus envelope protein structure in complex with a potent Human mAb

PDB ID 8dv6

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