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2xq3
From Proteopedia
(Difference between revisions)
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<StructureSection load='2xq3' size='340' side='right'caption='[[2xq3]], [[Resolution|resolution]] 3.50Å' scene=''> | <StructureSection load='2xq3' size='340' side='right'caption='[[2xq3]], [[Resolution|resolution]] 3.50Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xq3]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[2xq3]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Gloeobacter_violaceus_PCC_7421 Gloeobacter violaceus PCC 7421]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XQ3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XQ3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BR:BROMIDE+ION'>BR</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq3 OCA], [https://pdbe.org/2xq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xq3 RCSB], [https://www.ebi.ac.uk/pdbsum/2xq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xq3 ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xq3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xq3 OCA], [https://pdbe.org/2xq3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xq3 RCSB], [https://www.ebi.ac.uk/pdbsum/2xq3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xq3 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/GLIC_GLOVI GLIC_GLOVI] Cationic channel with similar permeabilities for Na(+) and K(+), that is activated by an increase of the proton concentration on the extracellular side. Displays no permeability for chloride ions. Shows slow kinetics of activation, no desensitization and a single channel conductance of 8 pS. Might contribute to adaptation to external pH change.<ref>PMID:17167423</ref> | |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Gloeobacter violaceus PCC 7421]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Bertozzi | + | [[Category: Bertozzi C]] |
| - | [[Category: Dutzler | + | [[Category: Dutzler R]] |
| - | [[Category: Hilf | + | [[Category: Hilf RJC]] |
| - | [[Category: Reiter | + | [[Category: Reiter A]] |
| - | [[Category: Trauner | + | [[Category: Trauner D]] |
| - | [[Category: Zimmermann | + | [[Category: Zimmermann I]] |
| - | + | ||
| - | + | ||
Current revision
Pentameric ligand gated ion channel GLIC in complex with Br-lidocaine
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