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5-hydroxytryptamine receptor 3D structures

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Current revision (07:06, 28 August 2024) (edit) (undo)
 
Line 7: Line 7:
**[[7e2z]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein – Cryo EM <br />
**[[7e2z]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein – Cryo EM <br />
**[[7e2y]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + serotonin– Cryo EM <br />
**[[7e2y]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + serotonin– Cryo EM <br />
 +
**[[8fy8]], [[8fye]], [[8fyl]], [[8fyx]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + drug – Cryo EM <br />
 +
**[[8fyt]] – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + LSD + cholesterol – Cryo EM <br />
 +
**[[8pjk]] – hHT1A + guanine nucleotide-binding protein + inositol derivative + cholesterol – Cryo EM <br />
 +
**[[8jsp]], [[8pkm]] – hHT61A+ guanine nucleotide-binding protein + scFv + drug – Cryo EM <br />
 +
*5-HT 1B
*5-HT 1B
Line 17: Line 22:
**[[7e32]] – hHT1D + guanine nucleotide-binding protein + Scfv + serotonin – Cryo EM <br />
**[[7e32]] – hHT1D + guanine nucleotide-binding protein + Scfv + serotonin – Cryo EM <br />
 +
 +
*5-HT 1E
 +
 +
**[[8ugy]], [[8uh3]] – hHT1E + guanine nucleotide-binding protein + drug – Cryo EM <br />
*5-HT 1F
*5-HT 1F
Line 24: Line 33:
*5-HT 2A
*5-HT 2A
-
**[[6a93]], [[6a94]], [[7vod]], [[7voe]], [[7wc5]], [[7wc7]], [[7wc8]], [[7wc9]] – hHT2A/cytochrome b562 (mutant) + drug<br />
+
**[[6a93]], [[6a94]], [[7vod]], [[7voe]], [[7wc5]], [[7wc7]], [[7wc8]], [[7wc9]], [[8jt8]] – hHT2A/cytochrome b562 (mutant) + drug<br />
**[[7wc4]] – hHT2A/cytochrome b562 (mutant) + serotonin<br />
**[[7wc4]] – hHT2A/cytochrome b562 (mutant) + serotonin<br />
**[[7wc6]] – hHT2A/cytochrome b562 (mutant) + LSD<br />
**[[7wc6]] – hHT2A/cytochrome b562 (mutant) + LSD<br />
**[[6wgt]] – hHT2A/cytochrome b562 + hallucinogen <br />
**[[6wgt]] – hHT2A/cytochrome b562 + hallucinogen <br />
**[[6wh4]] – hHT2A/cytochrome b562 + agonist<br />
**[[6wh4]] – hHT2A/cytochrome b562 + agonist<br />
-
**[[7ran]] – hHT2A + guanine nucleotide-binding protein + Scfv + agonist – Cryo EM <br />
+
**[[7ran]], [[8v6u]] – hHT2A + guanine nucleotide-binding protein + Scfv + agonist – Cryo EM <br />
 +
**[[8uwl]] – hHT2A + guanine nucleotide-binding protein + Scfv + drug – Cryo EM <br />
 +
 
*5-HT 2B
*5-HT 2B
Line 35: Line 46:
**[[4nc3]] – hHT2B/cytochrome b562 (mutant) <br />
**[[4nc3]] – hHT2B/cytochrome b562 (mutant) <br />
**[[4ib4]] – hHT2B/cytochrome b562 (mutant) + drug <br />
**[[4ib4]] – hHT2B/cytochrome b562 (mutant) + drug <br />
 +
**[[7srq]] – hHT2B + LSD – Cryo EM<br />
 +
**[[7srs]] – hHT2B + arrestin + antibody + LSD – Cryo EM<br />
 +
**[7srrl]] – hHT2B + guanine nucleotide-binding protein + Scfv + LSD – Cryo EM <br />
**[[5tvn]] – hHT2B/cytochrome b562 (mutant) + LSD <br />
**[[5tvn]] – hHT2B/cytochrome b562 (mutant) + LSD <br />
**[[5tud]] – hHT2B/cytochrome b562 (mutant) + antibody <br />
**[[5tud]] – hHT2B/cytochrome b562 (mutant) + antibody <br />
Line 42: Line 56:
**[[6bqg]], [[6bqh]] – hHT2C/cytochrome b562 (mutant) + ergotamine <br />
**[[6bqg]], [[6bqh]] – hHT2C/cytochrome b562 (mutant) + ergotamine <br />
 +
**[[8dpf]], [[8dph]], [[8dpi]] – hHT2C + guanine nucleotide-binding protein + scFv + drug – Cryo EM <br />
 +
**[[8dpg]] – hHT2C + guanine nucleotide-binding protein + scFv + serotonin derivative – Cryo EM <br />
*5-HT 3A
*5-HT 3A
 +
**[[8axd]] – hHT3A – Cryo EM<br />
 +
**[[8bla]], [[8blb]] – hHT3A + drug – Cryo EM<br />
**[[4pir]] – mHT3A + VHH15 - mouse<br />
**[[4pir]] – mHT3A + VHH15 - mouse<br />
-
**[[6be1]] – mHT3A – Cryo EM<br />
+
**[[6be1]], [[8bl8]], [[8c1w]], [[8c1z]], [[8c20]], [[8c21]] – mHT3A – Cryo EM<br />
**[[6his]] – mHT3A + drug<br />
**[[6his]] – mHT3A + drug<br />
-
**[[6np0]], [[6w1j]], [[6w1m]], [[6w1y]], [[6y1z]] – mHT3A + drug – Cryo EM<br />
+
**[[6np0]], [[6w1j]], [[6w1m]], [[6w1y]], [[6y1z]], [[8aw2]] – mHT3A + drug – Cryo EM<br />
-
**[[6dg7]], [[6dg8]], [[6hin]], [[6hio]], [[6hiq]] – mHT3A + serotonin – Cryo EM<br />
+
**[[8cc6]], [[8cc7]] – mHT3A + inhibitor – Cryo EM<br />
 +
**[[6dg7]], [[6dg8]], [[6hin]], [[6hio]], [[6hiq]], [[8frz]], [[8fsb]] – mHT3A + serotonin – Cryo EM<br />
**[[6y59]], [[6y5a]], [[6y5b]] – mHT3A (mutant) + serotonin – Cryo EM<br />
**[[6y59]], [[6y5a]], [[6y5b]] – mHT3A (mutant) + serotonin – Cryo EM<br />
 +
**[[8frx]], [[8frw]], [[8fsp]], [[8fsz]] – mHT3A + agonist – Cryo EM<br />
*5-HT 4
*5-HT 4
Line 65: Line 85:
**[[7xtb]] – hHT6 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM <br />
**[[7xtb]] – hHT6 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM <br />
 +
**[[8jlz]] – hHT6 + guanine nucleotide-binding protein + nanobody + agonist – Cryo EM <br />
 +
**[[7ys6]] – hHT6 + guanine nucleotide-binding protein + scFv + serotonin – Cryo EM <br />
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of 5-hydroxytryptamine receptor

Updated on 28-August-2024 - For a general description of the protein see 5-hydroxytryptamine receptor



Proteopedia Page Contributors and Editors (what is this?)

Michal Harel

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