3zwf

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Current revision (07:13, 1 May 2024) (edit) (undo)
 
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<StructureSection load='3zwf' size='340' side='right'caption='[[3zwf]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
<StructureSection load='3zwf' size='340' side='right'caption='[[3zwf]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3zwf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZWF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3zwf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3ZWF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3ZWF FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Ribonuclease_Z Ribonuclease Z], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.26.11 3.1.26.11] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwf OCA], [https://pdbe.org/3zwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zwf RCSB], [https://www.ebi.ac.uk/pdbsum/3zwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zwf ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3zwf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3zwf OCA], [https://pdbe.org/3zwf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3zwf RCSB], [https://www.ebi.ac.uk/pdbsum/3zwf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3zwf ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/RNZ1_HUMAN RNZ1_HUMAN]] Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.[HAMAP-Rule:MF_01818]
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[https://www.uniprot.org/uniprot/RNZ1_HUMAN RNZ1_HUMAN] Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.[HAMAP-Rule:MF_01818]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Ribonuclease Z]]
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[[Category: Allerston CK]]
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[[Category: Allerston, C K]]
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[[Category: Arrowsmith CH]]
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[[Category: Arrowsmith, C H]]
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[[Category: Berridge G]]
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[[Category: Berridge, G]]
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[[Category: Bountra C]]
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[[Category: Bountra, C]]
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[[Category: Burgess-Brown N]]
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[[Category: Burgess-Brown, N]]
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[[Category: Chaikuad A]]
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[[Category: Chaikuad, A]]
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[[Category: Chalk R]]
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[[Category: Chalk, R]]
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[[Category: Edwards A]]
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[[Category: Delft, F von]]
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[[Category: Elkins JM]]
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[[Category: Edwards, A]]
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[[Category: Gileadi C]]
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[[Category: Elkins, J M]]
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[[Category: Gileadi O]]
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[[Category: Gileadi, C]]
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[[Category: Krojer T]]
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[[Category: Gileadi, O]]
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[[Category: Latwiel SVA]]
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[[Category: Krojer, T]]
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[[Category: Savitsky P]]
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[[Category: Latwiel, S V.A]]
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[[Category: Vollmar M]]
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[[Category: Savitsky, P]]
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[[Category: Weigelt J]]
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[[Category: Vollmar, M]]
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[[Category: Von Delft F]]
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[[Category: Weigelt, J]]
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[[Category: Beta-lactamase]]
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[[Category: Catabolism]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Trna processing]]
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[[Category: Zinc-binding]]
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Current revision

Crystal structure of Human tRNase Z, short form (ELAC1).

PDB ID 3zwf

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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