Acetylcholinesterase 3D structures

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Current revision (10:18, 3 September 2024) (edit) (undo)
 
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*Acetylcholinesterase - AChE native
*Acetylcholinesterase - AChE native
-
**[[7e3d]] – hAChE - human <br />
+
**[[7e3d]], [[8dt2]] – hAChE - human <br />
**[[6o69]] – hAChE (mutant) <br />
**[[6o69]] – hAChE (mutant) <br />
**[[3lii]], [[4ey4]], [[4pqe]], [[5hq3]] – hAChE - recombinant human <br />
**[[3lii]], [[4ey4]], [[4pqe]], [[5hq3]] – hAChE - recombinant human <br />
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**[[1vzj]] – ''Tc''AChE tetramerization domain <br />
**[[1vzj]] – ''Tc''AChE tetramerization domain <br />
**[[1j06]], [[1maa]], [[5dti]] – mAChE - mouse <br />
**[[1j06]], [[1maa]], [[5dti]] – mAChE - mouse <br />
-
**[[1qo9]], [[6xys]] – ''Dm''AChE - ''Drosophila melanogaster'' <br />
+
**[[6xys]] – ''Dm''AChE - ''Drosophila melanogaster'' <br />
**[[1eea]], [[1c2b]], [[1c2o]] – AChE – Electric eel <br />
**[[1eea]], [[1c2b]], [[1c2o]] – AChE – Electric eel <br />
**[[5x61]], [[5ydh]], [[5ydi]] – mmAChE – malaria mosquito<br />
**[[5x61]], [[5ydh]], [[5ydi]] – mmAChE – malaria mosquito<br />
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**[[4bc0]], [[4bc1]] – mAChE + CBDP<br />
**[[4bc0]], [[4bc1]] – mAChE + CBDP<br />
**[[4a16]] – mAChE + huprine <br />
**[[4a16]] – mAChE + huprine <br />
-
**[[4ara]], [[4arb]], [[4a23]], [[4b7z]], [[4b80]], [[4b81]], [[4b82]], [[4b83]], [[4b84]], [[4b85]], [[4btl]], [[5fum]], [[5ehn]], [[5ehq]], [[5ehz]], [[5eia]], [[6td2]], [[7qak]], [[7qb4]], [[7qyn]], [[7r02]] - mAChE + inhibitor<br />
+
**[[4ara]], [[4arb]], [[4a23]], [[4b7z]], [[4b80]], [[4b81]], [[4b82]], [[4b83]], [[4b84]], [[4b85]], [[4btl]], [[5fum]], [[5ehn]], [[5ehq]], [[5ehz]], [[5eia]], [[6td2]], [[7qak]], [[7qb4]], [[7qyn]], [[7r02]], [[8orc]] - mAChE + inhibitor<br />
**[[2xuf]], [[2xug]], [[2xuh]], [[2xui]], [[2xuj]], [[2xuk]], [[2xuo]], [[2xup]], [[2xuq]] - mAChE (mutant) + inhibitor<br />
**[[2xuf]], [[2xug]], [[2xuh]], [[2xui]], [[2xuj]], [[2xuk]], [[2xuo]], [[2xup]], [[2xuq]] - mAChE (mutant) + inhibitor<br />
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**[[4ey5]] – hAChE + huperzine<br />
**[[4ey5]] – hAChE + huperzine<br />
-
**[[7e3i]] – hAChE + tacrine<br />
+
**[[7xn1]] – hAChE + tacrine<br />
**[[7e3h]] – hAChE + donepezil<br />
**[[7e3h]] – hAChE + donepezil<br />
-
**[[4m0e]], [[4m0f]], [[6wuv]], [[6wuz]], [[6wvc]], [[6wvp]], [[6wvq]], [[6xta]], [[6zwe]], [[7d9o]], [[7d9p]], [[7d9q]], [[7p1p]] - hAChE + inhibitor<br />
+
**[[4m0e]], [[4m0f]], [[6wuv]], [[6wuz]], [[6wvc]], [[6wvp]], [[6wvq]], [[6xta]], [[6zwe]], [[7d9o]], [[7d9p]], [[7d9q]], [[7p1p]], [[8aen]], [[8aev]] - hAChE + inhibitor<br />
**[[6o5v]], [[6o5s]], [[5o5r]], [[6u3p]], [[6u34]], [[6u37]], [[6nea]] - hAChE + oxime reactivator<br />
**[[6o5v]], [[6o5s]], [[5o5r]], [[6u3p]], [[6u34]], [[6u37]], [[6nea]] - hAChE + oxime reactivator<br />
**[[6o4x]] - hAChE + acridine derivative<br />
**[[6o4x]] - hAChE + acridine derivative<br />
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*''Drosophila melanogaster'' AChE active site inhibitors conjugating at the bottom of the active site gorge
*''Drosophila melanogaster'' AChE active site inhibitors conjugating at the bottom of the active site gorge
-
**[[1dx4]], [[1qon]], [[6xyu]], [[6xyy]] – ''Dm''AChE + tacrine derivative <br />
+
**[[6xyy]], [[6xyu]] – ''Dm''AChE + tacrine derivative <br />
*Other organisms AChE active site inhibitors
*Other organisms AChE active site inhibitors
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**[[5hf6]], [[5hf8]], [[5hf5]] – hAChE (mutant) + paraoxon<br />
**[[5hf6]], [[5hf8]], [[5hf5]] – hAChE (mutant) + paraoxon<br />
**[[5hfa]] – hAChE + paraoxon + 2-PAM<br />
**[[5hfa]] – hAChE + paraoxon + 2-PAM<br />
 +
**[[8dt4]], [[8dt5]], [[8dt7]] – hAChE + paraoxon + oxime<br />
**[[5hf9]] – hAChE + paraoxon + HI6<br />
**[[5hf9]] – hAChE + paraoxon + HI6<br />
**[[2wu3]] – mAChE + fenamiphos and HI-6 <br />
**[[2wu3]] – mAChE + fenamiphos and HI-6 <br />

Current revision

3D Structures of Acetylcholinesterase

Updated on 03-September-2024

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

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