7u8y
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics== | |
| - | + | <StructureSection load='7u8y' size='340' side='right'caption='[[7u8y]], [[Resolution|resolution]] 2.22Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7u8y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7U8Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7U8Y FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.22Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AZN:ALIZARIN+RED'>AZN</scene>, <scene name='pdbligand=MN:MANGANESE+(II)+ION'>MN</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7u8y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7u8y OCA], [https://pdbe.org/7u8y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7u8y RCSB], [https://www.ebi.ac.uk/pdbsum/7u8y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7u8y ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/TREX1_MOUSE TREX1_MOUSE] Exonuclease with a preference for double stranded DNA with mismatched 3' termini. May play a role in DNA repair.<ref>PMID:10391904</ref> <ref>PMID:11279105</ref> |
| - | [[Category: | + | == References == |
| - | [[Category: | + | <references/> |
| - | [[Category: | + | __TOC__ |
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mus musculus]] | ||
| + | [[Category: Harvey SE]] | ||
| + | [[Category: Hemphill WO]] | ||
| + | [[Category: Hollis T]] | ||
| + | [[Category: Perrino FW]] | ||
| + | [[Category: Salsbury FR]] | ||
| + | [[Category: Simpson SR]] | ||
| + | [[Category: Smalley TL]] | ||
Current revision
TREX1 Structural Studies Capture Small Molecule Inhibition and Implicate Novel DNA Dynamics
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