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7yph
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation== | |
| - | + | <StructureSection load='7yph' size='340' side='right'caption='[[7yph]], [[Resolution|resolution]] 3.68Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7yph]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Meiothermus_taiwanensis Meiothermus taiwanensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YPH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.68Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AGS:PHOSPHOTHIOPHOSPHORIC+ACID-ADENYLATE+ESTER'>AGS</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7yph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7yph OCA], [https://pdbe.org/7yph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7yph RCSB], [https://www.ebi.ac.uk/pdbsum/7yph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7yph ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A059VAZ3_9DEIN A0A059VAZ3_9DEIN] ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.[HAMAP-Rule:MF_01973] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Meiothermus taiwanensis]] | ||
| + | [[Category: Chang CI]] | ||
| + | [[Category: Ho MR]] | ||
| + | [[Category: Hsieh KY]] | ||
| + | [[Category: Kuo CI]] | ||
| + | [[Category: Lee SH]] | ||
| + | [[Category: Li S]] | ||
| + | [[Category: Wang CH]] | ||
| + | [[Category: Zhang K]] | ||
Current revision
Open-spiral pentamer of the substrate-free Lon protease with a Y224S mutation
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Categories: Large Structures | Meiothermus taiwanensis | Chang CI | Ho MR | Hsieh KY | Kuo CI | Lee SH | Li S | Wang CH | Zhang K
