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8aqp
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8aqp is ON HOLD Authors: Hubert, L.-S., Heine, A., Klebe, G. Description: Structure of Human Aldose Reductase Mutant A299G/L300A with a Citrate Mol...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Structure of Human Aldose Reductase Mutant A299G/L300A with a Citrate Molecule Bound in the Anion Binding Pocket== | |
| - | + | <StructureSection load='8aqp' size='340' side='right'caption='[[8aqp]], [[Resolution|resolution]] 0.96Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8aqp]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8AQP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8AQP FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 0.96Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr> |
| - | [[Category: Heine | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8aqp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8aqp OCA], [https://pdbe.org/8aqp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8aqp RCSB], [https://www.ebi.ac.uk/pdbsum/8aqp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8aqp ProSAT]</span></td></tr> |
| - | [[Category: Hubert | + | </table> |
| - | [[Category: Klebe | + | == Function == |
| + | [https://www.uniprot.org/uniprot/ALDR_HUMAN ALDR_HUMAN] Catalyzes the NADPH-dependent reduction of a wide variety of carbonyl-containing compounds to their corresponding alcohols with a broad range of catalytic efficiencies. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Heine A]] | ||
| + | [[Category: Hubert L-S]] | ||
| + | [[Category: Klebe G]] | ||
Current revision
Structure of Human Aldose Reductase Mutant A299G/L300A with a Citrate Molecule Bound in the Anion Binding Pocket
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