7vs3

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'''Unreleased structure'''
 
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The entry 7vs3 is ON HOLD until 2024-04-25
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==The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH==
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<StructureSection load='7vs3' size='340' side='right'caption='[[7vs3]], [[Resolution|resolution]] 2.59&Aring;' scene=''>
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Authors: Zhou, H., Wei, Z.Q., Zhang, L., Ren, Y.J., Ma, C.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7vs3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7VS3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7VS3 FirstGlance]. <br>
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Description: The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.595&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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[[Category: Zhou, H]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7vs3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7vs3 OCA], [https://pdbe.org/7vs3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7vs3 RCSB], [https://www.ebi.ac.uk/pdbsum/7vs3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7vs3 ProSAT]</span></td></tr>
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[[Category: Zhang, L]]
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</table>
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[[Category: Ren, Y.J]]
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== Function ==
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[[Category: Wei, Z.Q]]
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[https://www.uniprot.org/uniprot/CAPS1_RAT CAPS1_RAT] Calcium-binding protein involved in exocytosis of vesicles filled with neurotransmitters and neuropeptides. Probably acts upstream of fusion in the biogenesis or maintenance of mature secretory vesicles. Regulates catecholamine loading of DCVs. May specifically mediate the Ca(2+)-dependent exocytosis of large dense-core vesicles (DCVs) and other dense-core vesicles by acting as a PtdIns(4,5)P2-binding protein that acts at prefusion step following ATP-dependent priming and participates in DCVs-membrane fusion. However, it may also participate in small clear synaptic vesicles (SVs) exocytosis and it is unclear whether its function is related to Ca(2+) triggering.<ref>PMID:10792045</ref> <ref>PMID:1516133</ref> <ref>PMID:15312653</ref> <ref>PMID:9162085</ref> <ref>PMID:9697858</ref> <ref>PMID:9697859</ref>
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[[Category: Ma, C]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Rattus norvegicus]]
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[[Category: Ma C]]
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[[Category: Ren YJ]]
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[[Category: Wei ZQ]]
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[[Category: Zhang L]]
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[[Category: Zhou H]]

Current revision

The crystal structure of rat calcium-dependent activator protein for secretion (CAPS) C2PH

PDB ID 7vs3

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