7qam

<table><tr><td colspan='2'>[[7qam]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7QAM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7QAM FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7qam FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7qam OCA], [https://pdbe.org/7qam PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7qam RCSB], [https://www.ebi.ac.uk/pdbsum/7qam PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7qam ProSAT]</span></td></tr>

== Function ==

[[https://www.uniprot.org/uniprot/PGAM5_HUMAN PGAM5_HUMAN]] Displays phosphatase activity for serine/threonine residues, and, dephosphorylates and activates MAP3K5 kinase. Has apparently no phosphoglycerate mutase activity. May be regulator of mitochondrial dynamics. Substrate for a KEAP1-dependent ubiquitin ligase complex. Contributes to the repression of NFE2L2-dependent gene expression. Acts as a central mediator for programmed necrosis induced by TNF, by reactive oxygen species and by calcium ionophore.<ref>PMID:18387606</ref> <ref>PMID:19590015</ref> <ref>PMID:22265414</ref>

== References ==

<references/>

[[Category: Homo sapiens]]