Ankyrin repeat domain-containing protein
From Proteopedia
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== Disease == | == Disease == | ||
| - | Mutations in ARDCP 3 manifest as Bartsocas-Papas syndrome, a genetic disorder characterized by severe craniofacial and limb abnormalities<ref>PMID:29706531</ref>. | + | Mutations in '''ARDCP 3''' manifest as Bartsocas-Papas syndrome, a genetic disorder characterized by severe craniofacial and limb abnormalities<ref>PMID:29706531</ref>. |
== Structural highlights == | == Structural highlights == | ||
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== 3D structures of ankyrin repeat domain-containing protein == | == 3D structures of ankyrin repeat domain-containing protein == | ||
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[[Ankyrin repeat domain-containing protein 3D structures]] | [[Ankyrin repeat domain-containing protein 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
| - | == 3D structures of ankyrin repeat domain-containing protein == | ||
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| - | [[4nl9]] - hARDCP 3 SAM domain + hARDCP 14 SAM domain - human<br /> | ||
| - | [[5ybj]] - hARDCP 15 residues 1080-1329<br /> | ||
| - | [[5ybu]] - hARDCP 15 residues 1080-1329 + KIF21A peptide<br /> | ||
| - | [[4hbd]] - hARDCP 25 residues 578-832<br /> | ||
| - | [[6tmd]] - hARDCP 25 residues 583-832 (mutant)<br /> | ||
| - | [[5ybv]] - hARDCP 25 residues 578-832 + KIF21A peptide<br /> | ||
| - | [[4cym]] - hARDCP 27 residues 450-640 + RAB32<br /> | ||
| - | [[4cz2]] - hARDCP 27 residues 450-640 + RAB32 + GPPCP<br /> | ||
| - | [[4b93]] - hARDCP 27 residues 659-921 + VAMP7<br /> | ||
| - | [[5wni]] - mARDCP 3 residues 1-342 - mouse<br /> | ||
| - | [[5wnk]] - mARDCP 3 residues 1-342 (mutant)<br /> | ||
| - | [[5wnj]], [[5wnm]] - mARDCP 3 residues 1-342 (mutant) + cancer drug<br /> | ||
| - | [[5wnl]] - mARDCP 3 residues 1-342 (mutant) + staurosporine<br /> | ||
| - | [[6nxf]] - mARDCP 31 C-terminal + REC114<br /> | ||
| - | [[6tlh]] - mARDCP 47 residues 524-773 <br /> | ||
| - | [[5eid]], [[4tum]] - AtARDCP 2 residues 211-342 - ''Arabidopis thaliana''<br /> | ||
| - | [[6jd6]] - AtARDCP EMB56 + ARDCP<br /> | ||
| - | [[7ubz]] – ARDCP residues 1-230 + lipase effector – ''Enterobacter cloacae''<br /> | ||
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| - | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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- ↑ 1.0 1.1 Guo Q, Liao S, Zhu Z, Li Y, Li F, Xu C. Structural basis for the recognition of kinesin family member 21A (KIF21A) by the ankyrin domains of KANK1 and KANK2 proteins. J Biol Chem. 2017 Nov 28. pii: M117.817494. doi: 10.1074/jbc.M117.817494. PMID:29183992 doi:http://dx.doi.org/10.1074/jbc.M117.817494
- ↑ Huang CS, Oberbeck N, Hsiao YC, Liu P, Johnson AR, Dixit VM, Hymowitz SG. Crystal Structure of Ripk4 Reveals Dimerization-Dependent Kinase Activity. Structure. 2018 May 1;26(5):767-777.e5. doi: 10.1016/j.str.2018.04.002. Epub 2018, Apr 26. PMID:29706531 doi:http://dx.doi.org/10.1016/j.str.2018.04.002
