8eck

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "8eck" [edit=sysop:move=sysop])
Current revision (06:34, 19 June 2024) (edit) (undo)
 
(2 intermediate revisions not shown.)
Line 1: Line 1:
-
'''Unreleased structure'''
 
-
The entry 8eck is ON HOLD
+
==Gordonia phage Cozz==
 +
<SX load='8eck' size='340' side='right' viewer='molstar' caption='[[8eck]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[8eck]] is a 7 chain structure with sequence from [https://en.wikipedia.org/wiki/Gordonia_phage_Cozz Gordonia phage Cozz]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8ECK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8ECK FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8eck FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8eck OCA], [https://pdbe.org/8eck PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8eck RCSB], [https://www.ebi.ac.uk/pdbsum/8eck PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8eck ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/A0A160DFS7_9CAUD A0A160DFS7_9CAUD]
 +
<div style="background-color:#fffaf0;">
 +
== Publication Abstract from PubMed ==
 +
Many double-stranded DNA viruses, including tailed bacteriophages (phages) and herpesviruses, use the HK97-fold in their major capsid protein to make the capsomers of the icosahedral viral capsid. After the genome packaging at near-crystalline densities, the capsid is subjected to a major expansion and stabilization step that allows it to withstand environmental stresses and internal high pressure. Several different mechanisms for stabilizing the capsid have been structurally characterized, but how these mechanisms have evolved is still not understood. Using cryo-EM structure determination of 10 capsids, structural comparisons, phylogenetic analyses, and Alphafold predictions, we have constructed a detailed structural dendrogram describing the evolution of capsid structural stability within the actinobacteriophages. We show that the actinobacteriophage major capsid proteins can be classified into 15 groups based upon their HK97-fold.
-
Authors: Podgorski, J.M., White, S.J.
+
A structural dendrogram of the actinobacteriophage major capsid proteins provides important structural insights into the evolution of capsid stability.,Podgorski JM, Freeman K, Gosselin S, Huet A, Conway JF, Bird M, Grecco J, Patel S, Jacobs-Sera D, Hatfull G, Gogarten JP, Ravantti J, White SJ Structure. 2023 Mar 2;31(3):282-294.e5. doi: 10.1016/j.str.2022.12.012. Epub 2023 , Jan 16. PMID:36649709<ref>PMID:36649709</ref>
-
Description: Gordonia phage Cozz
+
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
-
[[Category: Unreleased Structures]]
+
</div>
-
[[Category: Podgorski, J.M]]
+
<div class="pdbe-citations 8eck" style="background-color:#fffaf0;"></div>
-
[[Category: White, S.J]]
+
== References ==
 +
<references/>
 +
__TOC__
 +
</SX>
 +
[[Category: Gordonia phage Cozz]]
 +
[[Category: Large Structures]]
 +
[[Category: Podgorski JM]]
 +
[[Category: White SJ]]

Current revision

Gordonia phage Cozz

8eck, resolution 2.60Å

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/8eck"
Personal tools