7q4n
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==transcription factor CDX2 bound to hydroxymethylated DNA== | |
| - | + | <StructureSection load='7q4n' size='340' side='right'caption='[[7q4n]], [[Resolution|resolution]] 3.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7q4n]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Q4N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Q4N FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5HC:2-DEOXY-5-(HYDROXYMETHYL)CYTIDINE+5-(DIHYDROGEN+PHOSPHATE)'>5HC</scene></td></tr> |
| - | [[Category: Morgunova | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7q4n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7q4n OCA], [https://pdbe.org/7q4n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7q4n RCSB], [https://www.ebi.ac.uk/pdbsum/7q4n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7q4n ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: | + | [https://www.uniprot.org/uniprot/CDX2_HUMAN CDX2_HUMAN] Involved in the transcriptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine. |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Morgunova E]] | ||
| + | [[Category: Popov A]] | ||
| + | [[Category: Taipale J]] | ||
| + | [[Category: Yin Y]] | ||
Current revision
transcription factor CDX2 bound to hydroxymethylated DNA
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