7ysv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==GluK1-1a extracellular domain captured in SYM2081 bound desensitized state== | |
| - | + | <StructureSection load='7ysv' size='340' side='right'caption='[[7ysv]], [[Resolution|resolution]] 8.01Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7ysv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7YSV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7YSV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 8.01Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7ysv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7ysv OCA], [https://pdbe.org/7ysv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7ysv RCSB], [https://www.ebi.ac.uk/pdbsum/7ysv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7ysv ProSAT]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/GRIK1_RAT GRIK1_RAT] Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. May be involved in the transmission of light information from the retina to the hypothalamus.<ref>PMID:16540562</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: Dhingra S]] | ||
| + | [[Category: Kumar J]] | ||
Current revision
GluK1-1a extracellular domain captured in SYM2081 bound desensitized state
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