8b1s
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==co-crystal of SUDV VP40 with salicylic acid== | |
| - | + | <StructureSection load='8b1s' size='340' side='right'caption='[[8b1s]], [[Resolution|resolution]] 1.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8b1s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sudan_ebolavirus Sudan ebolavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B1S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B1S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr> |
| - | [[Category: Becker | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b1s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b1s OCA], [https://pdbe.org/8b1s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b1s RCSB], [https://www.ebi.ac.uk/pdbsum/8b1s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b1s ProSAT]</span></td></tr> |
| - | [[Category: Werner | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VP40_EBOSU VP40_EBOSU] Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. May facilitate virus budding by interacting with the nucleocapsid and the plasma membrane. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. The hexamer form seems to be involved in budding. The octamer form binds RNA, and may play a role in genome replication (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sudan ebolavirus]] | ||
| + | [[Category: Becker S]] | ||
| + | [[Category: Heine A]] | ||
| + | [[Category: Klebe G]] | ||
| + | [[Category: Krapoth N]] | ||
| + | [[Category: Norris MJ]] | ||
| + | [[Category: Ollmann Saphire E]] | ||
| + | [[Category: Werner A-D]] | ||
Current revision
co-crystal of SUDV VP40 with salicylic acid
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