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8eh0

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m (Protected "8eh0" [edit=sysop:move=sysop])
Current revision (12:31, 4 October 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8eh0 is ON HOLD
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==Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with quinoline N-oxide==
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<StructureSection load='8eh0' size='340' side='right'caption='[[8eh0]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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Authors: Porter, N.J., Almhjell, P.J., Arnold, F.H.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8eh0]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermotoga_maritima Thermotoga maritima]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EH0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EH0 FirstGlance]. <br>
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Description: Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as E(A-A) and complexed with quinoline N-oxide
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0JO:2-{[(E)-{3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE]AMINO}PROP-2-ENOIC+ACID'>0JO</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=QOX:1-oxo-1lambda~5~-quinoline'>QOX</scene></td></tr>
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[[Category: Almhjell, P.J]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8eh0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8eh0 OCA], [https://pdbe.org/8eh0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8eh0 RCSB], [https://www.ebi.ac.uk/pdbsum/8eh0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8eh0 ProSAT]</span></td></tr>
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[[Category: Arnold, F.H]]
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</table>
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[[Category: Porter, N.J]]
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== Function ==
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[https://www.uniprot.org/uniprot/TRPB1_THEMA TRPB1_THEMA] The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Thermotoga maritima]]
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[[Category: Almhjell PJ]]
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[[Category: Arnold FH]]
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[[Category: Porter NJ]]

Current revision

Engineered tyrosine synthase (TmTyrS1) derived from T. maritima TrpB with Ser bound as the amino-acrylate intermediate and complexed with quinoline N-oxide

PDB ID 8eh0

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