4dev

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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4dev]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Butyrivibrio_proteoclasticus_B316 Butyrivibrio proteoclasticus B316]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DEV FirstGlance]. <br>
<table><tr><td colspan='2'>[[4dev]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Butyrivibrio_proteoclasticus_B316 Butyrivibrio proteoclasticus B316]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4DEV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4DEV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dev OCA], [https://pdbe.org/4dev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dev RCSB], [https://www.ebi.ac.uk/pdbsum/4dev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dev ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4dev FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4dev OCA], [https://pdbe.org/4dev PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4dev RCSB], [https://www.ebi.ac.uk/pdbsum/4dev PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4dev ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/E0RVY7_BUTPB E0RVY7_BUTPB]]
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[https://www.uniprot.org/uniprot/E0RVY7_BUTPB E0RVY7_BUTPB]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Butyrivibrio proteoclasticus is a significant component of the microbial population of the rumen of dairy cattle. It is a xylan-degrading organism whose genome encodes a large number of open reading frames annotated as fibre-degrading enzymes. We have determined the three-dimensional structure of Est2A, an acetyl xylan esterase from B. proteoclasticus, at 2.1 A resolution, along with the structure of an inactive mutant (H351A) at 2.0 A resolution. The structure reveals two domains - a C-terminal SGNH domain and an N-terminal jelly-roll domain typical of CE2 family structures. The structures are accompanied by experimentally determined enzymatic parameters against two model substrates, para-nitrophenyl acetate and para-nitrophenyl butyrate. The suite of fibre-degrading enzymes produced by B. proteoclasticus provides a rich source of new enzymes of potential use in industrial settings. Proteins 2013. (c) 2013 Wiley Periodicals, Inc.
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Structure and function of an acetyl xylan esterase (est2a) from the rumen bacterium Butyrivibrio proteoclasticus.,Till M, Goldstone DC, Attwood GT, Moon CD, Kelly WJ, Arcus VL Proteins. 2013 Jan 23. doi: 10.1002/prot.24254. PMID:23345031<ref>PMID:23345031</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 4dev" style="background-color:#fffaf0;"></div>
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== References ==
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<references/>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>

Current revision

An Acetyl Xylan Esterase (Est2A) from the Rumen Bacterium Butyrivibrio proteoclasticus.

PDB ID 4dev

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