This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
8b3c
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8b3c is ON HOLD Authors: Zhang, L., Groves, M.R. Description: chalcone synthase from Hordeum vulgare complexed with malonyl-CoA [[Category: Unrelea...) |
|||
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==chalcone synthase from Hordeum vulgare complexed with malonyl-CoA== | |
| - | + | <StructureSection load='8b3c' size='340' side='right'caption='[[8b3c]], [[Resolution|resolution]] 2.00Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8b3c]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B3C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B3C FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ERD:(2S)-2-(3,4-DIHYDROXYPHENYL)-5,7-DIHYDROXY-2,3-DIHYDRO-4H-CHROMEN-4-ONE'>ERD</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b3c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b3c OCA], [https://pdbe.org/8b3c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b3c RCSB], [https://www.ebi.ac.uk/pdbsum/8b3c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b3c ProSAT]</span></td></tr> |
| - | [[Category: Groves | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CHS2_HORVU CHS2_HORVU] The primary product of this enzyme is 4,2',4',6'-tetrahydroxychalcone (also termed naringenin-chalcone or chalcone) which can under specific conditions spontaneously isomerize into naringenin. Substrate preference is feruloyl-CoA = caffeoyl-CoA >> cinnamoyl-CoA. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Hordeum vulgare]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Groves MR]] | ||
| + | [[Category: Zhang L]] | ||
Current revision
chalcone synthase from Hordeum vulgare complexed with malonyl-CoA
| |||||||||||
