8b2u
From Proteopedia
(Difference between revisions)
| (One intermediate revision not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of SUDV VP40 in complex with salicylic acid== | |
| - | + | <StructureSection load='8b2u' size='340' side='right'caption='[[8b2u]], [[Resolution|resolution]] 1.80Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8b2u]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Sudan_ebolavirus Sudan ebolavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8B2U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8B2U FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SAL:2-HYDROXYBENZOIC+ACID'>SAL</scene></td></tr> |
| - | [[Category: Becker | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8b2u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8b2u OCA], [https://pdbe.org/8b2u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8b2u RCSB], [https://www.ebi.ac.uk/pdbsum/8b2u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8b2u ProSAT]</span></td></tr> |
| - | [[Category: Werner | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/VP40_EBOSU VP40_EBOSU] Promotes virus assembly and budding by interacting with host proteins of the multivesicular body pathway. May facilitate virus budding by interacting with the nucleocapsid and the plasma membrane. Specific interactions with membrane-associated GP and VP24 during the budding process may also occur. The hexamer form seems to be involved in budding. The octamer form binds RNA, and may play a role in genome replication (By similarity). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Sudan ebolavirus]] | ||
| + | [[Category: Becker S]] | ||
| + | [[Category: Heine A]] | ||
| + | [[Category: Klebe G]] | ||
| + | [[Category: Krapoth N]] | ||
| + | [[Category: Norris MJ]] | ||
| + | [[Category: Ollmann Saphire E]] | ||
| + | [[Category: Werner A-D]] | ||
Current revision
Crystal structure of SUDV VP40 in complex with salicylic acid
| |||||||||||
