8dwv
From Proteopedia
(Difference between revisions)
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| - | '''Unreleased structure''' | ||
| - | + | ==Full-length wild type SPOP== | |
| - | + | <StructureSection load='8dwv' size='340' side='right'caption='[[8dwv]], [[Resolution|resolution]] 3.60Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8dwv]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8DWV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8DWV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8dwv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8dwv OCA], [https://pdbe.org/8dwv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8dwv RCSB], [https://www.ebi.ac.uk/pdbsum/8dwv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8dwv ProSAT]</span></td></tr> | |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| - | [[Category: Cuneo | + | [https://www.uniprot.org/uniprot/SPOP_HUMAN SPOP_HUMAN] Inhibits IPF1/PDX1 transactivation of established target promoters, such as insulin, may be by recruiting a repressor complex (By similarity). In complex with CUL3, involved in ubiquitination of BMI1, H2AFY and DAXX, and probably also in ubiquitination and proteasomal degradation of Gli2 or Gli3.<ref>PMID:14528312</ref> <ref>PMID:15897469</ref> <ref>PMID:16524876</ref> |
| - | [[Category: Lo | + | == References == |
| - | [[Category: O | + | <references/> |
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Cuneo MJ]] | ||
| + | [[Category: Lo YH]] | ||
| + | [[Category: Mittag T]] | ||
| + | [[Category: O'Flynn B]] | ||
Current revision
Full-length wild type SPOP
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Categories: Homo sapiens | Large Structures | Cuneo MJ | Lo YH | Mittag T | O'Flynn B
