8ep0
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8ep0 is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Eag Kv channel with voltage sensor in the intermediate conformation== | |
| + | <StructureSection load='8ep0' size='340' side='right'caption='[[8ep0]], [[Resolution|resolution]] 4.90Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[8ep0]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Rattus_norvegicus Rattus norvegicus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EP0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EP0 FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 4.9Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ep0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ep0 OCA], [https://pdbe.org/8ep0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ep0 RCSB], [https://www.ebi.ac.uk/pdbsum/8ep0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ep0 ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/KCNH1_RAT KCNH1_RAT] Pore-forming (alpha) subunit of a voltage-gated delayed rectifier potassium channel. Channel properties may be modulated by subunit assembly, but not by cyclic nucleotides (By similarity). Mediates IK(NI) current in myoblasts (By similarity). Involved in the regulation of cell proliferation and differentiation, as adipogenic and osteogenic differentiation in bone marrow-derived mesenchymal stem cells (MSCs) (By similarity).[UniProtKB:O95259][UniProtKB:Q60603] | ||
| - | + | ==See Also== | |
| - | + | *[[Potassium channel 3D structures|Potassium channel 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Rattus norvegicus]] | ||
| + | [[Category: MacKinnon R]] | ||
| + | [[Category: Mandala VS]] | ||
Current revision
Eag Kv channel with voltage sensor in the intermediate conformation
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