8ep2

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(New page: '''Unreleased structure''' The entry 8ep2 is ON HOLD Authors: Mietzsch, M., McKenna, R. Description: The capsid structure of Aleutian Mink Disease Virus [[Category: Unreleased Structur...)
Current revision (06:38, 19 June 2024) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8ep2 is ON HOLD
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==The capsid structure of Aleutian Mink Disease Virus==
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<StructureSection load='8ep2' size='340' side='right'caption='[[8ep2]], [[Resolution|resolution]] 2.37&Aring;' scene=''>
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Authors: Mietzsch, M., McKenna, R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8ep2]] is a 60 chain structure with sequence from [https://en.wikipedia.org/wiki/Aleutian_mink_disease_virus Aleutian mink disease virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8EP2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8EP2 FirstGlance]. <br>
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Description: The capsid structure of Aleutian Mink Disease Virus
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.37&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8ep2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8ep2 OCA], [https://pdbe.org/8ep2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8ep2 RCSB], [https://www.ebi.ac.uk/pdbsum/8ep2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8ep2 ProSAT]</span></td></tr>
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[[Category: Mckenna, R]]
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</table>
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[[Category: Mietzsch, M]]
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_ADVG CAPSD_ADVG] Capsid protein self-assembles to form an icosahedral capsid with a T=1 symmetry, about 25 nm in diameter, and consisting of 60 copies of two size variants of the capsid proteins, VP1 (10% abundance) and VP2 (90% abundance), which differ by the presence of an N-terminal extension in the minor protein VP1. Capsid proteins are responsible for the attachment to host cell receptors. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. VP1 binds DNA and may therefore play a role in viral DNA encapsidation.<ref>PMID:11602751</ref> <ref>PMID:2842956</ref> <ref>PMID:8380073</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Aleutian mink disease virus]]
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[[Category: Large Structures]]
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[[Category: McKenna R]]
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[[Category: Mietzsch M]]

Current revision

The capsid structure of Aleutian Mink Disease Virus

PDB ID 8ep2

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