7xbz

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'''Unreleased structure'''
 
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The entry 7xbz is ON HOLD until Paper Publication
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==Crystal structure of Staphylococcus aureus ClpP in complex with R-ZG197==
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<StructureSection load='7xbz' size='340' side='right'caption='[[7xbz]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[7xbz]] is a 14 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XBZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XBZ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=D4E:(6S,9aS)-6-[(2S)-butan-2-yl]-8-[(1R)-1-naphthalen-1-ylethyl]-4,7-bis(oxidanylidene)-N-[4,4,4-tris(fluoranyl)butyl]-3,6,9,9a-tetrahydro-2H-pyrazino[1,2-a]pyrimidine-1-carboxamide'>D4E</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=MPD:(4S)-2-METHYL-2,4-PENTANEDIOL'>MPD</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xbz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xbz OCA], [https://pdbe.org/7xbz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xbz RCSB], [https://www.ebi.ac.uk/pdbsum/7xbz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xbz ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A0D1I3W4_STAAU A0A0D1I3W4_STAAU] Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.[HAMAP-Rule:MF_00444][RuleBase:RU000550]
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Authors: Wei, B.Y., Gan, J.H., Yang, C.-G.
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==See Also==
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*[[Clp protease 3D structures|Clp protease 3D structures]]
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Description: Crystal structure of Staphylococcus aureus ClpP in complex with R-ZG197
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__TOC__
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[[Category: Unreleased Structures]]
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</StructureSection>
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[[Category: Gan, J.H]]
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[[Category: Large Structures]]
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[[Category: Yang, C.-G]]
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[[Category: Staphylococcus aureus]]
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[[Category: Wei, B.Y]]
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[[Category: Gan JH]]
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[[Category: Wei BY]]
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[[Category: Yang C-G]]

Current revision

Crystal structure of Staphylococcus aureus ClpP in complex with R-ZG197

PDB ID 7xbz

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