1irr

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[[Image:1irr.gif|left|200px]]
 
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==Solution structure of paralytic peptide of the silkworm, Bombyx mori==
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The line below this paragraph, containing "STRUCTURE_1irr", creates the "Structure Box" on the page.
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<StructureSection load='1irr' size='340' side='right'caption='[[1irr]]' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1irr]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bombyx_mori Bombyx mori]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IRR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1IRR FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR, 20 models</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1irr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1irr OCA], [https://pdbe.org/1irr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1irr RCSB], [https://www.ebi.ac.uk/pdbsum/1irr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1irr ProSAT]</span></td></tr>
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{{STRUCTURE_1irr| PDB=1irr | SCENE= }}
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</table>
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== Function ==
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'''Solution structure of paralytic peptide of the silkworm, Bombyx mori'''
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[https://www.uniprot.org/uniprot/Q95YI2_BOMMO Q95YI2_BOMMO]
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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==Overview==
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Paralytic peptide of Bombyx mori (BmPP) is one of the multifunctional ENF-peptides; the name of "ENF" is the consensus N-terminal amino acid sequence of the family peptides. We revealed that BmPP significantly possesses growth-blocking activity and plasmatocyte-spreading activity and that its activity profiles are different from those of another ENF-family peptide, namely, the growth-blocking peptide of Pseudaletia separata (PsGBP). We also determined the NMR structures of BmPP and PsGBP under the same conditions, which revealed the structural differences of the first and second beta-turn regions between the two peptides. On the basis of our results, it can be considered that the tertiary structural difference in these peptides may cause their different profiles of growth-blocking activity.
Paralytic peptide of Bombyx mori (BmPP) is one of the multifunctional ENF-peptides; the name of "ENF" is the consensus N-terminal amino acid sequence of the family peptides. We revealed that BmPP significantly possesses growth-blocking activity and plasmatocyte-spreading activity and that its activity profiles are different from those of another ENF-family peptide, namely, the growth-blocking peptide of Pseudaletia separata (PsGBP). We also determined the NMR structures of BmPP and PsGBP under the same conditions, which revealed the structural differences of the first and second beta-turn regions between the two peptides. On the basis of our results, it can be considered that the tertiary structural difference in these peptides may cause their different profiles of growth-blocking activity.
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==About this Structure==
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Solution structure of paralytic peptide of silkworm, Bombyx mori.,Miura K, Kamimura M, Aizawa T, Kiuchi M, Hayakawa Y, Mizuguchi M, Kawano K Peptides. 2002 Dec;23(12):2111-6. PMID:12535689<ref>PMID:12535689</ref>
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1IRR is a [[Single protein]] structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1IRR OCA].
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==Reference==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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Solution structure of paralytic peptide of silkworm, Bombyx mori., Miura K, Kamimura M, Aizawa T, Kiuchi M, Hayakawa Y, Mizuguchi M, Kawano K, Peptides. 2002 Dec;23(12):2111-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12535689 12535689]
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</div>
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[[Category: Single protein]]
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<div class="pdbe-citations 1irr" style="background-color:#fffaf0;"></div>
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[[Category: Aizawa, T.]]
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== References ==
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[[Category: Hayakawa, Y.]]
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<references/>
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[[Category: Kamimura, M.]]
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__TOC__
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[[Category: Kawano, K.]]
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</StructureSection>
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[[Category: Kiuchi, M.]]
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[[Category: Bombyx mori]]
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[[Category: Miura, K.]]
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[[Category: Large Structures]]
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[[Category: Mizuguchi, M.]]
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[[Category: Aizawa T]]
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[[Category: Single beta sheet]]
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[[Category: Hayakawa Y]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:20:11 2008''
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[[Category: Kamimura M]]
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[[Category: Kawano K]]
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[[Category: Kiuchi M]]
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[[Category: Miura K]]
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[[Category: Mizuguchi M]]

Current revision

Solution structure of paralytic peptide of the silkworm, Bombyx mori

PDB ID 1irr

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