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8f2f
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==NMR solution structure of lambda-MeuKTx-1== | |
| - | + | <StructureSection load='8f2f' size='340' side='right'caption='[[8f2f]]' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8f2f]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mesobuthus_eupeus Mesobuthus eupeus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F2F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F2F FirstGlance]. <br> | |
| - | + | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene></td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f2f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f2f OCA], [https://pdbe.org/8f2f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f2f RCSB], [https://www.ebi.ac.uk/pdbsum/8f2f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f2f ProSAT]</span></td></tr> |
| - | [[Category: Craik | + | </table> |
| - | [[Category: Harvey | + | == Function == |
| + | [https://www.uniprot.org/uniprot/CLML_MESEU CLML_MESEU] Voltage-gated potassium channel (Kv) inhibitor (Ref.2). In addition it may increase intracellular calcium release through the activation of nuclear inositol 1,4,5-trisphosphate receptors (ITPR) of cardiomyocytes, thereby causing an increase in the contraction frequency of these cells (By similarity).[UniProtKB:P0DM29][UniProtKB:P59868] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Mesobuthus eupeus]] | ||
| + | [[Category: Craik DJ]] | ||
| + | [[Category: Harvey PJ]] | ||
Current revision
NMR solution structure of lambda-MeuKTx-1
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