8f2r

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'''Unreleased structure'''
 
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The entry 8f2r is ON HOLD
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==Human CCC complex==
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<StructureSection load='8f2r' size='340' side='right'caption='[[8f2r]], [[Resolution|resolution]] 3.12&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8f2r]] is a 10 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8F2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8F2R FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 3.12&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8f2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8f2r OCA], [https://pdbe.org/8f2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8f2r RCSB], [https://www.ebi.ac.uk/pdbsum/8f2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8f2r ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/COMD1_HUMAN COMD1_HUMAN] Promotes ubiquitination of NF-kappa-B subunit RELA and its subsequent proteasomal degradation. Down-regulates NF-kappa-B activity. Down-regulates SOD1 activity by interfering with its homodimerization. Plays a role in copper ion homeostasis. Can bind one copper ion per monomer. May function to facilitate biliary copper excretion within hepatocytes.<ref>PMID:14685266</ref> <ref>PMID:15799966</ref> <ref>PMID:16573520</ref> <ref>PMID:17309234</ref> <ref>PMID:17183367</ref> <ref>PMID:20048074</ref> <ref>PMID:20595380</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Berger I]]
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[[Category: Berger-Schaffitzel C]]
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[[Category: Borucu U]]
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[[Category: Butkovic R]]
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[[Category: Caruana NJ]]
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[[Category: Chen K]]
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[[Category: Chilton M]]
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[[Category: Collins BM]]
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[[Category: Croll TI]]
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[[Category: Cullen PJ]]
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[[Category: Derivery E]]
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[[Category: Ghai R]]
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[[Category: Hall RJ]]
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[[Category: Healy MD]]
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[[Category: Heesom KJ]]
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[[Category: Kadapalakere SY]]
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[[Category: Kato K]]
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[[Category: McConville C]]
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[[Category: McNally KE]]
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[[Category: Moody ERR]]
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[[Category: Nguyen THD]]
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[[Category: Palmer CS]]
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[[Category: Planelles-Herrero VJ]]
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[[Category: Ross J]]
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[[Category: Sacharz J]]
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[[Category: Saitoh S]]
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[[Category: Shaw S]]
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[[Category: Stroud DA]]
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[[Category: Williams TA]]

Current revision

Human CCC complex

PDB ID 8f2r

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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