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8hfv
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of CTSL in complex with K777== | |
| - | + | <StructureSection load='8hfv' size='340' side='right'caption='[[8hfv]], [[Resolution|resolution]] 2.10Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hfv]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HFV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HFV FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0IW:NALPHA-[(4-METHYLPIPERAZIN-1-YL)CARBONYL]-N-[(3S)-1-PHENYL-5-(PHENYLSULFONYL)PENTAN-3-YL]-L-PHENYLALANINAMIDE'>0IW</scene>, <scene name='pdbligand=CAC:CACODYLATE+ION'>CAC</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hfv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hfv OCA], [https://pdbe.org/8hfv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hfv RCSB], [https://www.ebi.ac.uk/pdbsum/8hfv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hfv ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/CATL1_HUMAN CATL1_HUMAN] Important for the overall degradation of proteins in lysosomes. | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Shao M]] | ||
| + | [[Category: Sun L]] | ||
| + | [[Category: Wang H]] | ||
| + | [[Category: Yang H]] | ||
Current revision
Crystal structure of CTSL in complex with K777
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Categories: Homo sapiens | Large Structures | Shao M | Sun L | Wang H | Yang H
