1j7j

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[[Image:1j7j.jpg|left|200px]]
 
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==Crystal Structure of the HPRT from Salmonella typhimurium==
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The line below this paragraph, containing "STRUCTURE_1j7j", creates the "Structure Box" on the page.
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<StructureSection load='1j7j' size='340' side='right'caption='[[1j7j]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1j7j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Salmonella_enterica_subsp._enterica_serovar_Typhimurium Salmonella enterica subsp. enterica serovar Typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J7J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1J7J FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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{{STRUCTURE_1j7j| PDB=1j7j | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1j7j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1j7j OCA], [https://pdbe.org/1j7j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1j7j RCSB], [https://www.ebi.ac.uk/pdbsum/1j7j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1j7j ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/HPRT_SALTY HPRT_SALTY] Acts preferentially on hypoxanthine; has very low activity towards guanine. Inactive towards xanthine (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/j7/1j7j_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1j7j ConSurf].
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<div style="clear:both"></div>
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'''Crystal Structure of the HPRT from Salmonella typhimurium'''
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==See Also==
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*[[Phosphoribosyltransferase 3D structures|Phosphoribosyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1J7J is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Salmonella_typhimurium Salmonella typhimurium]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1J7J OCA].
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[[Category: Large Structures]]
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[[Category: Hypoxanthine phosphoribosyltransferase]]
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[[Category: Salmonella enterica subsp. enterica serovar Typhimurium]]
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[[Category: Salmonella typhimurium]]
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[[Category: Eakin AE]]
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[[Category: Single protein]]
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[[Category: Focia PJ]]
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[[Category: Eakin, A E.]]
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[[Category: Lee CC]]
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[[Category: Focia, P J.]]
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[[Category: Spraggon G]]
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[[Category: Lee, C C.]]
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[[Category: Spraggon, G.]]
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[[Category: Glycosyltransferase]]
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[[Category: Nucleotide metabolism]]
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[[Category: Phosphoribosyltransferase]]
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[[Category: Purine salvage]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 20:52:53 2008''
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Current revision

Crystal Structure of the HPRT from Salmonella typhimurium

PDB ID 1j7j

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